What is Xarelto?
Xarelto (rivaroxaban) is an anticoagulant.
What is Xarelto used for?
Xarelto is used as a post-operative measure to prevent venous thromboembolism (prevention of blood clots), especially after a knee or hip surgery. If blood clots appear after such an operation, they can travel to lungs causing life-threatening effects.
How does Xarelto work?
Xarelto is an anticoagulant. It blocks the action of clotting factor Xa which is essential to the process of blood clotting. It thus prevents thrombosis (unwanted blood clots) in blood vessels.
How to use Xarelto
Xarelto should be used in the manner prescribed by a doctor. Taking the drug in larger amount or for longer time than prescribed may cause harmful effects. The dosage depends on your medical condition and response to treatment.
Xarelto is usually taken orally once a day, with or without food. Take the first tablet 6-10 hours after your operation and continue taking one every day after that.
The drug is usually prescribed for 5 weeks and 3 weeks for hip and knee surgery respectively.
Do not stop your dose unless your doctor asks you to.
Xarelto warnings and precautions
Xarelto is not administered to patients who are allergic to rivaroxaban. Patients who have any of the following conditions are advised against using this drug: severely reduced kidney function, severe liver disease which may cause bleeding, ongoing excessive bleeding, existence of body lesions at the risk of bleeding or bleeding in the brain within the last 6 months.
Since Xarelto contains lactose you should not take this drug if you have: galactose intolerance, glucose-galactose malabsorption, Lapp lactase deficiency.
Before taking the medication, inform your doctor about your medical conditions, especially if you have recently undergone a surgery of brain, spinal cord or eyes or if you have a bleeding disorder, active or a recent ulcer in stomach or intestine, retinopathy, very high and uncontrolled blood pressure. You may need a dose adjustment in such cases.
If you are given a catheter or injection into your spinal column for pain reduction or epidural or spinal anesthesia (as part of your surgery) take Xarelto before and after the removal of the catheter or administration of the injection. Also at the end of the anesthesia if you feel numbness or weakness in legs or you notice problems with your bowel or bladder inform your doctor immediately.
Xarelto should not be administered to children below 18 years.
Pregnant and lactating women are advised not to take this drug. Also inform your doctor immediately if you become pregnant while undergoing treatment with this drug.
What do I do if I have missed a Xarelto dose?
If you have missed a Xarelto dose, take it as soon as you remember. If, however, it is almost time for the next dose, the missed dose can be skipped. Do not take a double dose.
What do I do if I have taken a Xarelto overdose?
If you have taken an overdose of Xarelto, seek medical attention.
Some drugs which may interact with Xarelto are: oral antifungals such as ketoconazole, anti-inflammatory and pain relieving medicines such as aspirin, antiretroviral medicines for HIV/AIDS and other anticoagulants.
It is necessary to inform your doctor about all the prescription/non prescription drugs/herbal medicines that you are taking, before using Xarelto.
You should not start taking any new medicine, without consulting your doctor.
Xarelto side effects
Side effects from Xarelto include allergic reactions such as swelling of tongue, face, throat, hives, redness of skin etc. as well as some serious symptoms such as bleeding or oozing from surgical wound, excessive menstrual bleeding, bloody nose or bleeding gums that lasts for more than 5 minutes, blood in urine, hemorrhoids, signs of liver problem such as dark urine, pale stools, loss of appetite, vomiting, nausea, yellowing of skin; stiff, sore, painful joints; symptoms of unidentified bleeding such as headache, dizziness, weakness, paleness, or unexplained swelling.
Bruising and heavy flow during menstruation are some less serious side effects of Xarelto.