What is Prograf?
Prograf (tacrolimus) belongs to a class of drugs called immunosuppressants.
What is Prograf used for?
Prograf is used, with other medicines, to keep the body from rejecting the transplanted organs such as liver, kidney or heart.
How does Prograf work?
Prograf works by weakening body’s immune system so as to allow the body to accept the new organ.
How to use Prograf
Prograf should be taken in the manner prescribed by the doctor. Do not use it for longer periods or in larger amounts than recommended.
Prograf is usually taken every 12 hours. It can be taken with or without food. If you have an upset stomach or nausea, take the medicine with food. Remember to take the medicine at the same time each day.
You might be required to keep receiving injections of Prograf shortly after your transplant, until you are ready to take the pill form of the medicine.
Get your blood tested on a regular basis.
Prograf warnings and precautions
Do not take this medicine if you are allergic to tacrolimus or hydrogenated castor oil.
Prior to taking Prograf, tell your doctor if you have liver or kidney disease, high blood pressure, or if you have used cyclosporine (Sandimmune, Gengraf, Neoral) within the past 24 hours. You may need a dose adjustment.
Avoid being close to people suffering from contagious illnesses. Also avoid taking grapefruit or grapefruit juice while taking this medicine as it can increase the amount of certain medications in your bloodstream.
Do not receive a LIVE vaccine while you are being treated with this medication. Avoid exposure to sunlight or artificial Ultraviolet rays as it can increase the risk of skin cancer.
Before taking this drug, tell your doctor if you are using medicines to treat bowel disorder, pain or arthritis, antiviral medications, antibiotics taken in an injection form, or other medicines to prevent organ transplant rejection. Also tell him if you are receiving chemotherapy.<
What do I do if I have missed a Prograf dose?
If you have missed your Prograf dose, you can take the missed dose as soon as you remember but do not take it if it is time for your next dose.
What do I do if I have taken a Prograf overdose?
If you have taken a Prograf overdose, you should seek medical attention.
Before taking Prograf, consult your doctor if you are taking sirolimus (Rapamune), mycophenolate mofetil (CellCept), metoclopramide (Reglan), St John’s wort, omeprazole (Prilosec, Zegrid), lansoprazole (Prevacid); rifabutin (Mycobutin) or rifampin (Rimactane, Rifadin, Rifater); a potassium supplement or a water pill (diuretic); seizure medication such as phenobarbital (Luminal), carbamazepine (Carbatrol, Tegretol), phenytoin (Dilantin); birth control pills or hormone replacement; antifungal medicines such as itraconazole (Sporanox), ketoconazole (Nizoral), fluconazole (Diflucan), clotrimazole (Mycelex Troche), caspofungin (Cancidas), voriconazole (Vfend); HIV medication such as nelfinavir (Viracept), lopinavir/ritonavir (Kaletra), or ritonavir (Norvir); calcium channel blocker such as nifedipine (Adalat, Procardia), diltiazem (Cardizem, Dilacor XR, Tiazac), verapamil (Calan, Verelan), or nicardipine (Cardene); an antacid that contains aluminum or magnesium such as Rulox, Amphojel, Milk of
Prograf side effects
Prograf side effects include hives, breathing trouble, body ache, fever, chills, slow heart rate, mild shortness of breath, fast or pounding heartbeat, back ache, fatigue, weak pulse, pale skin, bruising, bleeding, muscle weakness, headache, confusion, numbness or tingly feeling, tremors, increased thirst or hunger, increased frequency of urination, decreased amount of urination, pain while urinating, blood in urine; problems with speech, vision, or coordination; swelling of face, tongue, lips, throat, feet or ankles, and other allergic reactions. If you get any of these side effects after using Prograf, contact your doctor.
Mild nausea, vomiting, stomach ache, constipation, diarrhea, loss of appetite, insomnia, skin rash or itching are some less serious side effects of Prograf.
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