Defend (Permethrin)

What is Defend?

What is Defend? Defend is a topical insecticide for dogs. Active ingredient: Permethrin (65% w/w). Permethrin is a Type I pyrethroid insecticide and repellant. Permethrin is in the class of pyrethroids: synthetic pyrethrins. Synthetic pyrethrins are laboratory-generated, not plant-based. Permethrins are more long lasting than plant-based pyrethrins, their natural counterparts. This compound is not an organophosphate. Mechanism of Action: Pyrethroids act as nervous system agents for insects, causing repeated over firing of nerves, accomplished through manipulation of the flow of sodium compounds out of cells. Pyrethroids are oil-soluble. They distribute themselves through the oils in an animal’s skin, and will diffuse across the animal’s entire body. Indications: Topical application for dogs only. Chemical agent is active to repel and kill ticks, fleas, and lice. Also reduces incidence of mosquito bites on dogs. Has a wide margin of safety. Appropriate for all breeds of dogs.

How to use Defend

Defend for dogs is applied to a single spot on the animal’s skin once per month. It provides continuous protection from certain pests for up to 30 days. Defend is only for use on dogs. Administer the treatment for mosquitoes and lice only when there is direct evidence of a problem for the pet. Reduces mosquito discomfort within 24 hours. Reduces lice within 7 days. May be used every 30 days to kill and repel fleas and ticks, whether or not there is direct evidence of infestation. DO NOT APPLY at intervals less than 7 days on any dog. Open the safety-sealed tube according to package directions. Part the animal’s hair and apply directly to the dog’s skin. Do not rub in. Administer 1 mL for dogs weighing 15 kg (33 pounds) or less. Apply 1 mL tube on the dog’s back, between the shoulder blades. Administer 2 mL for dogs weighing 15-30 kg (33-66 pounds). Apply 1mL between the shoulder blades, and 1 mL on the dog’s back at the base of the tail. Administer 4mL for dogs weighing more than 30 kg (66 pounds). Apply 2 mL between shoulder blades, and 2mL on the dog’s back at the base of the tail.

Defend warnings and precautions

DO NOT USE on sick, debilitated, pregnant, nursing, or very old dogs without first consulting a veterinarian. Do not use on puppies under 8 weeks of age, unless directed by a veterinarian. This medication is toxic to cats. Do not allow cats to come in contact with the medicine in any way. Cats who engage in close physical contact with dogs should not be allowed to interact with dogs that have been recently treated. This product is toxic to fish. Do not add directly to water. Do not clean fish equipment or aquariums immediately after using Defend. Always wash hands thoroughly after applying Defend, even if gloves have been worn. This product is harmful to humans if swallowed or absorbed through the skin. Keep out of reach of children. Do not allow product to come in contact with eyes, skin, and clothing. Wear gloves during application. Wash thoroughly after application. Avoid contact with the treated area on the dog until the skin is thoroughly dry. Keep children away from recently treated dogs until the treated area is completely dry. If swallowed, do not induce vomiting. Contact poison control immediately.

What do I do if I have missed a Defend dose?

In the event of an overdose, consult a veterinarian immediately. Retain the product information. Defend is intended to be applied in intervals of 30 days. If a dosage is missed, resume treatment, and calculate thirty days from that date. Defend should NEVER, uner any circumstances, be applied more frequently than seven-day intervals.

Defend interactions

Potential drug interactions are not documented, but Defend should not be used on any dogs who are receiving other medications except as directed by a veterinarian.

Defend side effects

Sensitivity to the product is reported in some cases. Increased itching, rash, redness, and skin sensitivity may be possible Defend side effects. Observe the animal closely following treatment. If side effects occur, bathe the dog with mild soap and rinse thoroughly with plenty of clean water. Discontinue use. Consult a veterinarian.