Combipatch (Estradiol/Norethindrone)

What is Combipatch?

Combipatch is a combination transdermal patch consisting of an estrogen and a progestin. It comes under the class of medicines known as hormone replacement therapy.

What is Combipatch used for?

Combipatch is used to prevent the symptoms caused by menopause. These symptoms include hot flashes, chills, sweating, and uterine bleeding.

How does Combipatch work?

Combipatch starts its mechanism by releasing hormones into the blood through skin.

How to use Combipatch

A 28-day treatment cycle consists of 8 patches. You have to apply one patch twice a week. Once the sequence of 28-day period is complete, you can start the next cycle with a new package of patches.

Tear open the pack and do not use scissors. After opening, apply the patch to the selective area instantaneously and do not touch the adhesive side. Gently press the patch with the help of your fingers for about 10 seconds.

The patch has to be applied on a dry and clean area of your skin. Your skin should not be oily, damaged, or irritated. Also, apply the patch to the buttocks and abdomen. Avoid applying it to the area where clothing rubs off the patch or where skin is very hairy.

Do not apply Combipatch to the same site in a row but make sure that it is applied on the same area of your body.

Combipatch warnings and precautions

What do I do if I have missed a Combipatch dose?

If you have missed your Combipatch dose you should take it as soon as possible. Do not apply two patches at one time.

What do I do if I have taken a Combipatch overdose?

If you have taken Combipatch overdose you should call your doctor right away.

Combipatch interactions

Before taking this medicine, consult your doctor if you are already taking drugs like barbiturates, lamotrigine, meprobamate, phenylbutazone, rifabutin, rifampin, phenytoin, topiramate, carbamazepine, warfarin, antidiabetic agents, or blood pressure lowering medication.

Combipatch side effects

The possible side effects of Combipatch are back pain, bloating or gas, excess of vaginal secretions, breast tenderness, darkening of skin around the sites where patch is used, depression, dizziness, fluid retention, flu like symptoms, muscle ache, nausea, feeling of tiredness, itching, spots, burning, redness, swelling near the areas of skin where patch is used, vaginal itching.

Call your doctor immediately if side effects like migraine, breast pain, and swelling of feet and lower legs occur. Very rare side effects of Combipatch are breast lumps, abdominal tenderness, nausea, vomiting, persistent upper abdominal pain, easy bruising, exceptionally heavy periods, jaundice, pain or feeling of pressure in pelvis, rapid weight gain, or discharge from nipples.